Assay Detail
Functional
CHEMBL911486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of 2-arachidonylglycerol production
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.95 | 5.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379637 | — | — | 1 | 5.95 |
| CHEMBL212197 | — | — | 1 | - |
| CHEMBL292821 | — | — | 1 | - |
| CHEMBL215781 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379637 | — | EC50 | = | 1120.0 | nM | 5.95 |
| CHEMBL212197 | — | EC50 | - | — | - | |
| CHEMBL292821 | — | EC50 | - | — | - | |
| CHEMBL215781 | — | EC50 | > | 10000.0 | nM | - |