Assay Detail
Functional
CHEMBL913588
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human T-47D cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.20 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221655 | — | — | 1 | 7.72 |
| CHEMBL220692 | — | — | 1 | 7.70 |
| CHEMBL221654 | — | — | 1 | 7.35 |
| CHEMBL221955 | — | — | 1 | 7.03 |
| CHEMBL218097 | — | — | 1 | 6.71 |
| CHEMBL376909 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221655 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL220692 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL221654 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL221955 | — | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL218097 | — | IC50 | = | 197.0 | nM | 6.71 |
| CHEMBL376909 | — | IC50 | = | 198.0 | nM | 6.70 |