Assay Detail
Binding
CHEMBL916483
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Binding affinity to adenosine A2A receptor in rat brain striatum
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Neuroprotective principles from Gastrodia elata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 5.33 |
| Ki | 2 | 5.10 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224024 | — | — | 2 | 5.58 |
| CHEMBL224380 | — | — | 2 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224024 | — | Ki | = | 2620.0 | nM | 5.58 |
| CHEMBL224024 | — | IC50 | = | 4660.0 | nM | 5.33 |
| CHEMBL224380 | — | Ki | = | 24100.0 | nM | 4.62 |
| CHEMBL224380 | — | IC50 | = | 42900.0 | nM | 4.37 |