Assay Detail
Binding
CHEMBL918101
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Displacement of [3H]DPDPE from delta opioid receptor in rat brain synaptosomes P2 fraction
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Synaptosomes |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 10.11 | 10.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388320 | — | — | 1 | 10.46 |
| CHEMBL2369958 | — | — | 1 | 10.22 |
| CHEMBL225479 | — | — | 1 | 9.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388320 | — | Ki | = | 0.035 | nM | 10.46 |
| CHEMBL2369958 | — | Ki | = | 0.06 | nM | 10.22 |
| CHEMBL225479 | — | Ki | = | 0.22 | nM | 9.66 |