Assay Detail
Binding
CHEMBL923883
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Inhibition of amylo-1,6-glucosidase
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.71 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80254 | — | — | 1 | 5.08 |
| CHEMBL312653 | — | — | 1 | 5.01 |
| CHEMBL407337 | — | — | 1 | 4.96 |
| CHEMBL259905 | — | — | 1 | 4.96 |
| CHEMBL247666 | — | — | 1 | 4.92 |
| CHEMBL259721 | — | — | 1 | 4.80 |
| CHEMBL1208974 | SALACINOL | — | 1 | 4.32 |
| CHEMBL408355 | — | — | 1 | 4.32 |
| CHEMBL406972 | — | — | 1 | 4.00 |
| CHEMBL405957 | — | — | 1 | - |
| CHEMBL406973 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80254 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL312653 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL407337 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL259905 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL247666 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL259721 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL1208974 | SALACINOL | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL408355 | — | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL406972 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL405957 | — | IC50 | - | — | - | |
| CHEMBL406973 | — | IC50 | = | 200000.0 | nM | - |