Assay Detail
Binding
CHEMBL923889
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Inhibition of rat isomaltase
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.63 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405957 | — | — | 1 | 7.40 |
| CHEMBL406973 | — | — | 1 | 7.10 |
| CHEMBL259721 | — | — | 1 | 6.19 |
| CHEMBL80254 | — | — | 1 | 5.24 |
| CHEMBL1208974 | SALACINOL | — | 1 | 5.24 |
| CHEMBL247666 | — | — | 1 | 4.16 |
| CHEMBL312653 | — | — | 1 | 4.05 |
| CHEMBL408278 | — | — | 1 | - |
| CHEMBL259905 | — | — | 1 | - |
| CHEMBL408355 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405957 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL406973 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL259721 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL80254 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL1208974 | SALACINOL | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL247666 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL312653 | — | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL408278 | — | IC50 | = | 1000000.0 | nM | - |
| CHEMBL259905 | — | IC50 | = | 150000.0 | nM | - |
| CHEMBL408355 | — | IC50 | = | 730000.0 | nM | - |