Assay Detail
Functional
CHEMBL925854
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Effect on glucose consumption in digitonin permeablized Trypanosoma cruzi
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200262 | — | — | 1 | 6.21 |
| CHEMBL370662 | — | — | 1 | 5.92 |
| CHEMBL55886 | — | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200262 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL370662 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL55886 | — | IC50 | = | 10300.0 | nM | 4.99 |