Assay Detail
Binding
CHEMBL926253
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]PDBu from PKCalpha C1A domain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis, conformational analysis, and biological evaluation of 1-hexylindolactam-V10 as a selective activator for novel protein kinase C isozymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.03 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL399981 | — | — | 1 | 8.24 |
| CHEMBL27266 | INDOLACTUM | — | 1 | 7.68 |
| CHEMBL401369 | — | — | 1 | 5.17 |
| CHEMBL206866 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL399981 | — | Ki | = | 5.8 | nM | 8.24 |
| CHEMBL27266 | INDOLACTUM | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL401369 | — | Ki | = | 6700.0 | nM | 5.17 |
| CHEMBL206866 | — | Ki | > | 10000.0 | nM | - |