Assay Detail
ADMET
CHEMBL928990
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Inhibition of CYP3A4
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.88 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253528 | — | — | 1 | 5.96 |
| CHEMBL429850 | — | — | 1 | 5.80 |
| CHEMBL401895 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253528 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL429850 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL401895 | — | IC50 | > | 6000.0 | nM | - |