Assay Detail
Binding
CHEMBL930947
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Displacement of [3H]PDBu from PKCgamma C1B domain
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and physicochemical properties of new fluorescent ligands of protein kinase C isozymes focused on CH/pi interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.22 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | — | 1 | 6.68 |
| CHEMBL271403 | — | — | 1 | 6.65 |
| CHEMBL261387 | — | — | 1 | 5.96 |
| CHEMBL441897 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL271403 | — | Ki | = | 225.0 | nM | 6.65 |
| CHEMBL261387 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL441897 | — | Ki | = | 2580.0 | nM | 5.59 |