Assay Detail
Binding
CHEMBL934554
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to delta opioid receptor in Sprague-Dawley rat brain membrane
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 9.86 | 10.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109390 | — | — | 1 | 10.46 |
| CHEMBL408975 | — | — | 1 | 10.18 |
| CHEMBL407957 | — | — | 1 | 9.94 |
| CHEMBL258704 | — | — | 1 | 9.84 |
| CHEMBL260127 | — | — | 1 | 9.70 |
| CHEMBL258458 | — | — | 1 | 9.55 |
| CHEMBL259917 | — | — | 1 | 9.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109390 | — | Ki | = | 0.035 | nM | 10.46 |
| CHEMBL408975 | — | Ki | = | 0.066 | nM | 10.18 |
| CHEMBL407957 | — | Ki | = | 0.114 | nM | 9.94 |
| CHEMBL258704 | — | Ki | = | 0.145 | nM | 9.84 |
| CHEMBL260127 | — | Ki | = | 0.199 | nM | 9.70 |
| CHEMBL258458 | — | Ki | = | 0.283 | nM | 9.55 |
| CHEMBL259917 | — | Ki | = | 0.443 | nM | 9.35 |