Assay Detail
ADMET
CHEMBL939876
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Binding affinity to CYP2D6
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Antagonists of the calcium receptor I. Amino alcohol-based parathyroid hormone secretagogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.95 | 7.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504479 | — | — | 1 | 7.44 |
| CHEMBL2112075 | — | — | 1 | 7.35 |
| CHEMBL523475 | — | — | 1 | 7.12 |
| CHEMBL486278 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504479 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL2112075 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL523475 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL486278 | — | IC50 | = | 1260.0 | nM | 5.90 |