Assay Detail
Functional
CHEMBL944107
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Antiproliferative activity against human HL60 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An antiproliferative bis-prenylated quinone from the New Zealand brown alga Perithalia capillaris.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.52 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL403123 | — | — | 1 | 6.47 |
| CHEMBL150457 | p-Xyloquinone | — | 1 | 6.19 |
| CHEMBL251493 | — | — | 1 | 5.57 |
| CHEMBL249651 | — | — | 1 | 5.25 |
| CHEMBL403339 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL403123 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL150457 | p-Xyloquinone | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL251493 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL249651 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL403339 | — | IC50 | = | 73000.0 | nM | 4.14 |