Assay Detail
ADMET
CHEMBL945182
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2D6
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL486045 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL486045 | — | IC50 | = | 250.0 | nM | 6.60 |