Assay Detail
ADMET
CHEMBL950339
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Inhibition of CYP2D6
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
[4-(Phenoxy)pyridin-3-yl]methylamines: a new class of selective noradrenaline reuptake inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.84 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270791 | — | — | 1 | 6.21 |
| CHEMBL273208 | — | — | 1 | 5.47 |
| CHEMBL403363 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270791 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL273208 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL403363 | — | IC50 | - | — | - |