Assay Detail
Binding
CHEMBL954230
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from rat 5HT2A receptor expressed in mouse NIH3T3 cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
'Hybrid' benzofuran-benzopyran congeners as rigid analogs of hallucinogenic phenethylamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.39 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL520449 | — | — | 1 | 9.00 |
| CHEMBL101008 | — | — | 1 | 9.00 |
| CHEMBL482702 | — | — | 1 | 8.51 |
| CHEMBL519145 | — | — | 1 | 8.44 |
| CHEMBL482675 | — | — | 1 | 8.35 |
| CHEMBL520133 | — | — | 1 | 8.28 |
| CHEMBL482704 | — | — | 1 | 8.08 |
| CHEMBL482703 | — | — | 1 | 7.96 |
| CHEMBL6607 | BROLAMFETAMINE | 2.0 | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL520449 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL101008 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL482702 | — | Ki | = | 3.1 | nM | 8.51 |
| CHEMBL519145 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL482675 | — | Ki | = | 4.5 | nM | 8.35 |
| CHEMBL520133 | — | Ki | = | 5.3 | nM | 8.28 |
| CHEMBL482704 | — | Ki | = | 8.4 | nM | 8.08 |
| CHEMBL482703 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL6607 | BROLAMFETAMINE | Ki | = | 13.0 | nM | 7.89 |