Assay Detail
Functional
CHEMBL957935
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against mouse WEHI164 cells after 72 hrs by MTT conversion assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | WEHI-164 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiproliferative oleanane saponins from Meryta denhamii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 6.01 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1425 | MERCAPTOPURINE ANHYDROUS | 4.0 | 1 | 7.82 |
| CHEMBL486881 | — | — | 1 | 6.47 |
| CHEMBL507138 | — | — | 1 | 5.77 |
| CHEMBL506188 | — | — | 1 | 5.47 |
| CHEMBL507155 | — | — | 1 | 5.34 |
| CHEMBL499677 | — | — | 1 | 5.16 |
| CHEMBL448367 | — | — | 1 | - |
| CHEMBL452712 | — | — | 1 | - |
| CHEMBL509910 | — | — | 1 | - |
| CHEMBL524337 | — | — | 1 | - |
| CHEMBL502666 | — | — | 1 | - |
| CHEMBL449916 | — | — | 1 | - |
| CHEMBL505247 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1425 | MERCAPTOPURINE ANHYDROUS | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL486881 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL507138 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL506188 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL507155 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL499677 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL448367 | — | IC50 | - | — | - | |
| CHEMBL452712 | — | IC50 | - | — | - | |
| CHEMBL509910 | — | IC50 | - | — | - | |
| CHEMBL524337 | — | IC50 | - | — | - | |
| CHEMBL502666 | — | IC50 | - | — | - | |
| CHEMBL449916 | — | IC50 | - | — | - | |
| CHEMBL505247 | — | IC50 | - | — | - |