Assay Detail
Functional
CHEMBL963825
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Cytotoxicity against human A2780 cells after 72 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of new-generation taxoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.24 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL467163 | — | — | 1 | 9.60 |
| CHEMBL126916 | — | — | 1 | 9.36 |
| CHEMBL450955 | — | — | 1 | 9.12 |
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL467163 | — | IC50 | = | 0.25 | nM | 9.60 |
| CHEMBL126916 | — | IC50 | = | 0.44 | nM | 9.36 |
| CHEMBL450955 | — | IC50 | = | 0.76 | nM | 9.12 |
| CHEMBL428647 | PACLITAXEL | IC50 | = | 1.38 | nM | 8.86 |