Assay Detail
ADMET
CHEMBL964176
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP2D6 by microplate-based direct fluorometric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473763 | — | — | 1 | 5.89 |
| CHEMBL460542 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473763 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL460542 | — | IC50 | < | 1000.0 | nM | - |