Assay Detail
ADMET
CHEMBL969592
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Inhibition of human CYP2C9
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.08 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL467720 | — | — | 1 | 5.32 |
| CHEMBL467114 | — | — | 1 | 5.10 |
| CHEMBL513491 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL467720 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL467114 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL513491 | — | IC50 | = | 15000.0 | nM | 4.82 |