Assay Detail
Binding
CHEMBL972651
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Inhibition of adenylate binding site of Photinus pyralis luciferase by quantitative high throughput screening
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Photinus pyralis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.85 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL261118 | — | — | 1 | 6.30 |
| CHEMBL411085 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL261118 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL411085 | — | IC50 | = | 4000.0 | nM | 5.40 |