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Assay Detail

CHEMBL977871

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Functional
Antiproliferative effect against human HL60 cells after 69 hrs
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Bioactive compounds from Peperomia pellucida.
Xu S, Li N, Ning MM, Zhou CH, Yang QR, Wang MW.
J Nat Prod (2006) 69 : 247 -250
PubMed 16499324 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 5.81 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL44657 ETOPOSIDE 4.0 1 6.68
CHEMBL491522 1 5.85
CHEMBL521941 PEPEROMIN E 1 5.75
CHEMBL490349 1 4.97
CHEMBL225191 PEPEROMIN A 1 -
CHEMBL523790 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL44657 ETOPOSIDE IC50 = 210.0 nM 6.68
CHEMBL491522 IC50 = 1400.0 nM 5.85
CHEMBL521941 PEPEROMIN E IC50 = 1800.0 nM 5.75
CHEMBL490349 IC50 = 10800.0 nM 4.97
CHEMBL225191 PEPEROMIN A IC50 - -
CHEMBL523790 IC50 - -