Compound Detail
CHEMBL225191
PEPEROMIN A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL225191 |
| Name | PEPEROMIN A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UYKJDDXZIMXQNB-SMDDNHRTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names
Molecular Properties
414.4
MW (Da)
3.10
ALogP
8
HBA
0
HBD
81.7
PSA (Ų)
0.69
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 5.28 | 5.28 | 5300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 5300.0 | nM | 5.28 | Antiviral activity against on HIV1 3b infected C8166 cells assessed as syncytial... | 17291043 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16724842 | 10.1021/np0600447 | Unchecked | 6 |
| 19559609 | 10.1016/j.bmcl.2009.06.029 | A549 | 5 |
| 16724842 | 10.1021/np0600447 | A549 | 2 |
| 16499324 | 10.1021/np050457s | HL-60 | 2 |
| 16499324 | 10.1021/np050457s | MCF7 | 2 |
| 16499324 | 10.1021/np050457s | HeLa | 2 |
| 17291043 | 10.1021/np0605236 | Human immunodeficiency virus 1 | 1 |
| 17291043 | 10.1021/np0605236 | Unchecked | 1 |
| 17291043 | 10.1021/np0605236 | C8166 | 1 |
| 16724842 | 10.1021/np0600447 | ADMET | 1 |
| 16724842 | 10.1021/np0600447 | WI-38 VA13 | 1 |
| 16724842 | 10.1021/np0600447 | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine