Assay Detail
Functional
CHEMBL978327
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Cytotoxicity against mouse P388 cells after 72 hrs by MTT method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
10-Phenyl-[12]-cytochalasins Z7, Z8, and Z9 from the marine-derived fungus Spicaria elegans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.69 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL494856 | CYTOCHALASIN E | — | 1 | 7.03 |
| CHEMBL498454 | — | — | 1 | 4.25 |
| CHEMBL497529 | — | — | 1 | 4.12 |
| CHEMBL500120 | CYTOCHALASIN K | — | 1 | 4.05 |
| CHEMBL498455 | CYTOCHALASIN Z9 | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL494856 | CYTOCHALASIN E | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL498454 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL497529 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL500120 | CYTOCHALASIN K | IC50 | = | 89000.0 | nM | 4.05 |
| CHEMBL498455 | CYTOCHALASIN Z9 | IC50 | = | 99000.0 | nM | 4.00 |