Assay Detail
ADMET
CHEMBL979034
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Inhibition of CYP2D6
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
N-Benzyl-N-(pyrrolidin-3-yl)carboxamides as a new class of selective dual serotonin/noradrenaline reuptake inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.66 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL477374 | — | — | 1 | 4.75 |
| CHEMBL513139 | — | — | 1 | 4.66 |
| CHEMBL476954 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL477374 | — | IC50 | = | 17600.0 | nM | 4.75 |
| CHEMBL513139 | — | IC50 | = | 21800.0 | nM | 4.66 |
| CHEMBL476954 | — | IC50 | = | 27100.0 | nM | 4.57 |