Assay Detail
Functional
CHEMBL979809
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Antitrypanosomal activity against Trypanosoma cruzi Y bloodstream trypomastigotes after 24 hrs by light microscope
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cellular effects of reversed amidines on Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.48 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL447705 | — | — | 1 | 7.82 |
| CHEMBL450746 | — | — | 1 | 7.05 |
| CHEMBL416108 | — | — | 1 | 6.35 |
| CHEMBL46010 | — | — | 1 | 4.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL447705 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL450746 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL416108 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL46010 | — | IC50 | = | 19400.0 | nM | 4.71 |