Assay Detail
Functional
CHEMBL979810
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Antitrypanosomal activity against Trypanosoma cruzi Y amastigotes after 24 hrs by light microscope
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cellular effects of reversed amidines on Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.88 | 8.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL450746 | — | — | 1 | 8.07 |
| CHEMBL416108 | — | — | 1 | 6.62 |
| CHEMBL447705 | — | — | 1 | 5.94 |
| CHEMBL46010 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL450746 | — | IC50 | = | 8.6 | nM | 8.07 |
| CHEMBL416108 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL447705 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL46010 | — | IC50 | > | 10600.0 | nM | - |