Assay Detail
Functional
CHEMBL980499
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma cruzi in mouse peritoneal macrophages
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiparasitic activity of some xanthones and biflavonoids from the root bark of Garcinia livingstonei.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.86 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL454538 | GARCILIVIN A | — | 1 | 5.40 |
| CHEMBL482023 | — | — | 1 | 5.24 |
| CHEMBL188061 | — | — | 1 | 5.16 |
| CHEMBL479289 | — | — | 1 | 5.10 |
| CHEMBL500482 | — | — | 1 | 4.46 |
| CHEMBL499445 | GARCIVILIN C | — | 1 | 4.41 |
| CHEMBL463023 | VOLKENSIFLAVONE | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL454538 | GARCILIVIN A | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL482023 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL188061 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL479289 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL500482 | — | IC50 | = | 34700.0 | nM | 4.46 |
| CHEMBL499445 | GARCIVILIN C | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL463023 | VOLKENSIFLAVONE | IC50 | = | 56000.0 | nM | 4.25 |