Assay Detail
Functional
CHEMBL980945
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Antifungal activity against Fusarium culmorum by Almar blue assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Fusarium culmorum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pestalachlorides A-C, antifungal metabolites from the plant endophytic fungus Pestalotiopsis adusta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.69 | 6.05 |
| MIC | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470091 | PESTALACHLORIDE A | — | 2 | 6.05 |
| CHEMBL513378 | PESTALACHLORIDE B | — | 2 | 5.33 |
| CHEMBL470095 | PESTALACHLORIDE C | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470091 | PESTALACHLORIDE A | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL513378 | PESTALACHLORIDE B | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL470091 | PESTALACHLORIDE A | MIC | = | 7200.0 | nM | - |
| CHEMBL470095 | PESTALACHLORIDE C | IC50 | > | 118500.0 | nM | - |
| CHEMBL470095 | PESTALACHLORIDE C | MIC | > | 236900.0 | nM | - |
| CHEMBL513378 | PESTALACHLORIDE B | MIC | = | 49000.0 | nM | - |