Assay Detail
Binding
CHEMBL983874
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]neomonapride from dopamine D2 receptor in rat corpus striatum
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.52 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27559 | — | — | 1 | 7.54 |
| CHEMBL480149 | — | — | 1 | 7.01 |
| CHEMBL480525 | — | — | 1 | 6.64 |
| CHEMBL480524 | — | — | 1 | 6.64 |
| CHEMBL520573 | — | — | 1 | 6.19 |
| CHEMBL520262 | — | — | 1 | 6.14 |
| CHEMBL480526 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27559 | — | Ki | = | 28.5 | nM | 7.54 |
| CHEMBL480149 | — | Ki | = | 97.0 | nM | 7.01 |
| CHEMBL480525 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL480524 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL520573 | — | Ki | = | 641.0 | nM | 6.19 |
| CHEMBL520262 | — | Ki | = | 731.0 | nM | 6.14 |
| CHEMBL480526 | — | Ki | = | 3340.0 | nM | 5.48 |