Assay Detail
Binding
CHEMBL992473
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]5-HT from human SERT
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent serotonin transporter (CHEMBL228) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The molecular interactions of buspirone analogues with the serotonin transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.50 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL485540 | — | — | 1 | 8.10 |
| CHEMBL485541 | — | — | 1 | 7.30 |
| CHEMBL520024 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL485540 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL485541 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL520024 | — | IC50 | = | 80.0 | nM | 7.10 |