Assay Detail
Functional
CHEMBL994635
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplatelet activity against rabbit platelets assessed as collagen-induced platelet aggregation by turbidimetric method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel antiplatelet constituents from formosan moraceous plants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.46 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL465167 | KAZINOL A | — | 1 | 4.68 |
| CHEMBL115452 | BROUSSOCHALCONE A | — | 1 | 4.65 |
| CHEMBL463093 | CYCLOARTOCARPIN A | — | 1 | 4.62 |
| CHEMBL461821 | HETEROPHYLLIN | — | 1 | 4.31 |
| CHEMBL467194 | ARTOCARPANONE | — | 1 | 4.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL465167 | KAZINOL A | IC50 | = | 20700.0 | nM | 4.68 |
| CHEMBL115452 | BROUSSOCHALCONE A | IC50 | = | 22400.0 | nM | 4.65 |
| CHEMBL463093 | CYCLOARTOCARPIN A | IC50 | = | 23700.0 | nM | 4.62 |
| CHEMBL461821 | HETEROPHYLLIN | IC50 | = | 48700.0 | nM | 4.31 |
| CHEMBL467194 | ARTOCARPANONE | IC50 | = | 90700.0 | nM | 4.04 |