Compound Detail
CHEMBL463093
CYCLOARTOCARPIN A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL463093 |
| Name | CYCLOARTOCARPIN A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FUOITKFXHPXSCA-SOFGYWHQSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names
Molecular Properties
434.5
MW (Da)
5.95
ALogP
6
HBA
2
HBD
89.1
PSA (Ų)
0.49
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.73 | 4.675 | 18500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 18500.0 | nM | 4.73 | Antiplatelet activity against rabbit platelets assessed as arachidonic acid-indu... | 8864236 |
| NON-PROTEIN TARGET | IC50 | = | 23700.0 | nM | 4.62 | Antiplatelet activity against rabbit platelets assessed as collagen-induced plat... | 8864236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8864236 | 10.1021/np960376j | NON-PROTEIN TARGET | 6 |
| 15165133 | 10.1021/np030467y | NON-PROTEIN TARGET | 2 |
| 15165133 | 10.1021/np030467y | A549 | 1 |
| 15165133 | 10.1021/np030467y | MCF7 | 1 |
| 15165133 | 10.1021/np030467y | 1A9 | 1 |
| 15165133 | 10.1021/np030467y | HCT-8 | 1 |
| 15165133 | 10.1021/np030467y | CAKI-1 | 1 |
| 15165133 | 10.1021/np030467y | SK-MEL-2 | 1 |
| 15165133 | 10.1021/np030467y | PC-3 | 1 |
| 15165133 | 10.1021/np030467y | MDA-MB-231 | 1 |
| 15165133 | 10.1021/np030467y | KB | 1 |
Data from ChEMBL 36 via Core Engine