Assay Detail
Functional
CHEMBL995252
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Antimicrobial activity against Escherichia coli CGMCC 1.2340
7
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive asterric acid derivatives from the Antarctic ascomycete fungus Geomyces sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.44 | 5.98 |
| MIC | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL372795 | STREPTOMYCIN | 4.0 | 2 | 5.98 |
| CHEMBL507180 | GEOMYCIN C | — | 2 | 4.89 |
| CHEMBL499049 | ETHYL ASTERRATE | — | 1 | - |
| CHEMBL501396 | GEOMYCIN A | — | 1 | - |
| CHEMBL499873 | BUTYL ASTERRATE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL372795 | STREPTOMYCIN | IC50 | = | 1050.0 | nM | 5.98 |
| CHEMBL507180 | GEOMYCIN C | IC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL507180 | GEOMYCIN C | MIC | = | 30300.0 | nM | - |
| CHEMBL372795 | STREPTOMYCIN | MIC | = | 11200.0 | nM | - |
| CHEMBL499049 | ETHYL ASTERRATE | IC50 | > | 50000.0 | nM | - |
| CHEMBL501396 | GEOMYCIN A | IC50 | > | 50000.0 | nM | - |
| CHEMBL499873 | BUTYL ASTERRATE | IC50 | > | 50000.0 | nM | - |