Assay Detail
Functional
CHEMBL995834
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Antimicrobial activity against Aspergillus fumigatus ATCC 10894
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aspergillus fumigatus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pestalofones A-E, bioactive cyclohexanone derivatives from the plant endophytic fungus Pestalotiopsis fici.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 6.05 |
| MIC | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL443191 | PESTALOFONE E | — | 2 | 6.05 |
| CHEMBL522168 | PESTALOFONE C | — | 2 | 5.96 |
| CHEMBL106 | FLUCONAZOLE | 4.0 | 2 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL443191 | PESTALOFONE E | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL522168 | PESTALOFONE C | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL106 | FLUCONAZOLE | IC50 | = | 7350.0 | nM | 5.13 |
| CHEMBL522168 | PESTALOFONE C | MIC | = | 35300.0 | nM | - |
| CHEMBL443191 | PESTALOFONE E | MIC | = | 31200.0 | nM | - |
| CHEMBL106 | FLUCONAZOLE | MIC | = | 163400.0 | nM | - |