Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL997488

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PKC gamma
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Protein kinase C gamma type (CHEMBL2938)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
Fujioka T, Kashiwada Y, Kilkuskie RE, Cosentino LM, Ballas LM, Jiang JB, Janzen WP, Chen IS, Lee KH.
J Nat Prod (1994) 57 : 243 -247
PubMed 8176401 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.28 4.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL502585 1 4.43
CHEMBL509553 1 4.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL502585 IC50 = 37000.0 nM 4.43
CHEMBL509553 IC50 = 74000.0 nM 4.13