Assay Detail
Binding
CHEMBL999151
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of horse serum BChE by Ellman's reaction
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Equus caballus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.83 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455600 | — | — | 1 | 4.95 |
| CHEMBL499836 | NOSTOCARBOLINE | — | 2 | 4.88 |
| CHEMBL1555 | GALANTAMINE HYDROBROMIDE | 4.0 | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455600 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL499836 | NOSTOCARBOLINE | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL1555 | GALANTAMINE HYDROBROMIDE | IC50 | = | 16900.0 | nM | 4.77 |
| CHEMBL499836 | NOSTOCARBOLINE | IC50 | = | 19400.0 | nM | 4.71 |