Assay Detail
Functional
CHEMBL999152
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Cytotoxicity against mouse P388 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discorhabdin W, the first dimeric discorhabdin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.44 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL509693 | DISCORHABDIN W | — | 1 | 7.08 |
| CHEMBL462946 | DISCORHABDIN B | — | 1 | 7.06 |
| CHEMBL463158 | — | — | 1 | 6.29 |
| CHEMBL553245 | DISCORHABDIN L | — | 1 | 5.96 |
| CHEMBL540660 | DISCORHABDIN D | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL509693 | DISCORHABDIN W | IC50 | = | 84.0 | nM | 7.08 |
| CHEMBL462946 | DISCORHABDIN B | IC50 | = | 87.0 | nM | 7.06 |
| CHEMBL463158 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL553245 | DISCORHABDIN L | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL540660 | DISCORHABDIN D | IC50 | = | 1600.0 | nM | 5.80 |