Compound Detail
CHEMBL100642
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL100642 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PHXGHVYEHFIZEC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
424.6
MW (Da)
4.32
ALogP
4
HBA
0
HBD
60.2
PSA (Ų)
0.59
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL5136 | IC50 | 7.75 | 7.75 | 18.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | IC50 | = | 18.0 | nM | 7.75 | Inhibition of PAF-induced platelet aggregation | 8411016 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8411016 | 10.1021/jm00072a019 | Platelet-activating factor receptor | 3 |
Data from ChEMBL 36 via Core Engine