Compound Detail
CHEMBL1084938
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Basic Information
| ChEMBL ID | CHEMBL1084938 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WXFDRTZMBRMEOV-PFONDFGASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
276.3
MW (Da)
2.97
ALogP
3
HBA
2
HBD
58.2
PSA (Ų)
0.73
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HT-22 CHEMBL614316 | EC50 | 4.51 | 4.51 | 30800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HT-22 | EC50 | = | 30800.0 | nM | 4.51 | Cytoprotective activity against tunicamycin-induced cell death in mouse HT22 cel... | 29122482 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29122482 | 10.1016/j.bmcl.2017.10.069 | HT-22 | 7 |
| 27106709 | 10.1016/j.bmcl.2016.03.111 | Serine/threonine-protein kinase 17B | 1 |
Data from ChEMBL 36 via Core Engine