Compound Detail
CHEMBL1090054
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Basic Information
| ChEMBL ID | CHEMBL1090054 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CKKANQHIQPKNFI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
263.3
MW (Da)
1.71
ALogP
4
HBA
1
HBD
49.8
PSA (Ų)
0.90
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HT-22 CHEMBL614316 | EC50 | 5.59 | 5.59 | 2560.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HT-22 | EC50 | = | 2560.0 | nM | 5.59 | Neuroprotective activity against glutamate-mediated oxidative stress-induced cel... | 20045220 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20045220 | 10.1016/j.ejmech.2009.12.006 | HT-22 | 3 |
Data from ChEMBL 36 via Core Engine