Compound Detail
CHEMBL1093484
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Basic Information
| ChEMBL ID | CHEMBL1093484 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BXIBCAKDSIOWAN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
260.3
MW (Da)
3.45
ALogP
2
HBA
0
HBD
34.1
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 17-beta-hydroxysteroid dehydrogenase type 3 CHEMBL4234 | IC50 | 5.57 | 5.57 | 2700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 17-beta-hydroxysteroid dehydrogenase type 3 | IC50 | = | 2700.0 | nM | 5.57 | Inhibition of 17beta-HSD3 in human testis microsomes | 20346654 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20346654 | 10.1016/j.bmcl.2010.02.089 | 17-beta-hydroxysteroid dehydrogenase type 3 | 1 |
Data from ChEMBL 36 via Core Engine