Compound Detail

CHEMBL1096401

UDP TRISODIUM

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O=c1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])[O-])[C@@H](O)[C@H]2O)c(=O)[nH]1.[Na+].[Na+].[Na+]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL1096401
Name	UDP TRISODIUM
Phase	Preclinical
Structure Type	MOL
InChI Key	GFASEGWJDXDCKZ-LLWADOMFSA-K
Parent Compound	CHEMBL130266
Active Moiety	CHEMBL130266

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

404.2

MW (Da)

-2.62

ALogP

HBA

HBD

217.8

PSA (Å²)

0.27

QED

Ro5 Violations

Rot. Bonds

First in Class Prodrug

EC50 3 meas. best 5.94

Target	Type	Best pChEMBL	Mean pChEMBL	Best (nM)	# Data
Uracil nucleotide/cysteinyl leukotriene receptor CHEMBL1075162	EC50	5.94	5.94	1140.0	1
Unchecked CHEMBL612545	EC50	5.94	5.73	1140.0	2

Top measurements by pChEMBL value

Target	Type	Rel.	Value	Units	pChEMBL	Assay	PubMed
Unchecked	EC50	=	1140.0	nM	5.94	Agonist activity at P2Y receptor by [35S]GTPgammaS binding assay	20394377
Uracil nucleotide/cysteinyl leukotriene receptor	EC50	=	1140.0	nM	5.94	Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as indu...	20394377
Unchecked	EC50	=	3000.0	nM	5.52	Agonist activity at human GPR17 R255I mutant expressed in human 1321N1 cells ass...	20394377

PubMed	DOI	Target Context	# Activities
20394377	10.1021/jm901691y	Unchecked	2
20394377	10.1021/jm901691y	Uracil nucleotide/cysteinyl leukotriene receptor	1
17417631	10.1038/nchembio873	Unchecked	1

Data from ChEMBL 36 via Core Engine