Compound Detail
CHEMBL11148
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Basic Information
| ChEMBL ID | CHEMBL11148 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KBZDKGYYUHQRTH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
275.4
MW (Da)
2.40
ALogP
3
HBA
1
HBD
47.6
PSA (Ų)
0.92
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melatonin receptor CHEMBL2094268 | Ki | 7.21 | 7.21 | 62.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melatonin receptor | Ki | = | 62.2 | nM | 7.21 | Binding affinity against ovine pars tuberalis melatonin receptor using 2-[125I]-... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00175-8 | Melatonin receptor | 2 |
Data from ChEMBL 36 via Core Engine