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Compound Detail

CHEMBL1159892

PROCINOLOL
🧪 Phase II
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🧪 Phase II
CC(C)NCC(O)COc1ccccc1C1CC1

Basic Information

ChEMBL ID CHEMBL1159892
Name PROCINOLOL
Phase Phase II
Structure Type MOL
InChI Key RTAGQMIEWAAKMO-UHFFFAOYSA-N

Known Names

Procinolol SD 2124-01 SD-2124-01
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
3
Known Names

Molecular Properties

249.3
MW (Da)
2.30
ALogP
3
HBA
2
HBD
41.5
PSA (Ų)
0.78
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Racemic
USAN Stem -olol

Extended Properties

Molecular Formula C15H23NO2
MW 249.35
Aromatic Rings 1
Heavy Atoms 18
NP-Likeness -0.33

Activity Summary

Kd 1 meas. best 9.41

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL3373
Kd 9.41 9.41 0.4 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
2993621 10.1021/jm00147a037 Beta-2 adrenergic receptor 2

Data from ChEMBL 36 via Core Engine