Beta-2 adrenergic receptor · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt Q28044. Use UniProt Q28044 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q28044 as the stable identity anchor, then attach disease evidence before program review.
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt Q28044. Sequence length is 418 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-2 adrenergic receptor as ChEMBL target CHEMBL3373, mapped to UniProt Q28044. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-2 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q28044 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-2 adrenergic receptor |
| UniProt Accession | Q28044 |
| Component Type | Protein |
| Sequence Length | 418 aa |
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt Q28044. Sequence length is 418 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1159892 | 9.41 | Kd | 0.39 | Clinical |
| CHEMBL1159723 | 9.2 | Kd | 0.63 | Preclinical |
| CHEMBL1671 | 9.05 | Kd | 0.89 | Approved |
| CHEMBL266195 | 8.53 | IC50 | 2.98 | Clinical |
| CHEMBL1159714 | 7.99 | Kd | 10.23 | Preclinical |
| CHEMBL6920 | 7.99 | Kd | 10.23 | Preclinical |
| CHEMBL26917 | 7.75 | IC50 | 17.6 | Preclinical |
| CHEMBL1159889 | 7.75 | Kd | 17.78 | Preclinical |
| CHEMBL1788270 | 7.7 | IC50 | 20.1 | Preclinical |
| CHEMBL1159888 | 7.66 | Kd | 21.88 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 54 | 6.1 |
| cell membrane format | 6 | 9 | 6.9 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |