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Compound Detail

CHEMBL1160788

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N[C@@H]1CCc2cc(O)c(O)cc2C1

Basic Information

ChEMBL ID CHEMBL1160788
Phase Preclinical
Structure Type MOL
InChI Key ASXGAOFCKGHGMF-MRVPVSSYSA-N
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

179.2
MW (Da)
0.91
ALogP
3
HBA
3
HBD
66.5
PSA (Ų)
0.52
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C10H13NO2
MW 179.22
Aromatic Rings 1
Heavy Atoms 13
NP-Likeness 1.03

Activity Summary

Kd 4 meas. best 6.92

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
D(2) dopamine receptor
CHEMBL339
Kd 6.92 6.18 120.0 4

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
10956209 10.1021/jm990526y D(2) dopamine receptor 4

Data from ChEMBL 36 via Core Engine