Compound Detail
CHEMBL1161520
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Basic Information
| ChEMBL ID | CHEMBL1161520 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TVURRHSHRRELCG-ZDUSSCGKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
305.8
MW (Da)
2.73
ALogP
4
HBA
4
HBD
72.7
PSA (Ų)
0.61
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL2056 | Kd | 5.74 | 5.74 | 1818.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Kd | = | 1818.0 | nM | 5.74 | Equilibrium dissociation constant against recombinant Dopamine receptor D1A expr... | 8632409 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8632409 | 10.1021/jm950447w | D(1A) dopamine receptor | 3 |
Data from ChEMBL 36 via Core Engine