Compound Detail
CHEMBL116198
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL116198 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HTGJLPLFDGFCBG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
436.3
MW (Da)
4.90
ALogP
5
HBA
1
HBD
72.2
PSA (Ų)
0.49
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL5136 | IC50 | 8.4 | 8.4 | 4.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | IC50 | = | 4.0 | nM | 8.4 | Antagonistic activity was tested against Platelet-Activating Factor-induced aggr... | 7658438 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7658438 | 10.1021/jm00018a011 | Platelet-activating factor receptor | 2 |
Data from ChEMBL 36 via Core Engine