Compound Detail
CHEMBL1162545
GLYOXYLATE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1162545 |
| Name | GLYOXYLATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HHLFWLYXYJOTON-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
74.0
MW (Da)
-0.73
ALogP
2
HBA
1
HBD
54.4
PSA (Ų)
0.33
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 4-hydroxy-tetrahydrodipicolinate synthase CHEMBL4083 | Ki | 4.8 | 4.8 | 16000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 4-hydroxy-tetrahydrodipicolinate synthase | Ki | = | 16000.0 | nM | 4.8 | Inhibition of Escherichia coli DHDPS | 18977662 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C9MD00107G | 4-hydroxy-tetrahydrodipicolinate synthase | 2 |
| 18977662 | 10.1016/j.bmc.2008.10.026 | 4-hydroxy-tetrahydrodipicolinate synthase | 1 |
| 11101640 | 10.1111/j.1469-7793.2000.00285.x | Monocarboxylate transporter 4 | 1 |
| 37252106 | 10.1039/d3md00058c | Putative citrate synthase 2 | 1 |
| 38128237 | 10.1016/j.ejmech.2023.116058 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine